Spleen-Restricted Posttransplant Lymphoproliferative Disorder in the First Year After Kidney Transplant - A Case Report

• Type: Another Publication in an International Scientific Journal
• Date: 2022

Authors

Rodrigues, AC (Author) Other; Fernandes, S (Author) Other; Bustorff, M (Author) Other; Nunes, AT (Author) Other; Ferreira, I (Author) Other; Tavares, I (Author) FMUP; Rocha, A (Author) Other; Carneiro, A (Author) Other; Sampaio, SN (Author) Other

Journal

Title: Transplantation Proceedings

ISSN: 0041-1345

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 1 Citation

Scopus

Other information

Authenticus ID: P-00W-KBE

DOI: 10.1016/j.transproceed.2022.03.005

Abstract (EN): Posttransplant lymphoproliferative disorders (PTLDs) are a feared complication after transplant. They are mostly of B cell origin and are frequently Epstein-Barr virus (EBV)-positive, particu-larly in early onset PTLD. Later on, non-B and EBV-negative PTLD are increasingly reported. EBV seronegative receptors (particularly when paired with an EBV seropositive donor) together with the net degree of immunosuppression-a concept often difficult to quantify-are the most consistently described risk factors for the development of PTLD. Conversely, its association with a particular immunosuppressive agent or other virus, namely cytomegalovirus (CMV) infec-tion or disease, has been inconsistently reported. We present a challenging case where an EBV negative monomorphic peripheric T-cell lymphoma was diagnosed in the first year after kidney in a with a recent of CMV disease from a resistant strain.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3