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MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network

Title
MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network
Type
Article in International Scientific Journal
Year
2020
Authors
Migliori, GB
(Author)
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Tiberi, S
(Author)
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Zumla, A
(Author)
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Petersen, E
(Author)
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Chakaya, JM
(Author)
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Wejse, C
(Author)
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Muñoz Torrico, M
(Author)
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Alffenaar, JW
(Author)
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Schaaf, HS
(Author)
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Marais, BJ
(Author)
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Cirillo, DM
(Author)
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Alagna, R
(Author)
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Rendon, A
(Author)
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Pontali, E
(Author)
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Piubello, A
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Figueroa, J
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Ferlazzo, G
(Author)
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García Basteiro, A
(Author)
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Centis, R
(Author)
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Visca, D
(Author)
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D'Ambrosio, L
(Author)
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Sotgiu, G
(Author)
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Arkub, TA
(Author)
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Akkerman, OW
(Author)
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Aleksa, A
(Author)
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Belilovski, E
(Author)
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Bernal, E
(Author)
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Blanc, FX
(Author)
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Boeree, M
(Author)
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Borisov, S
(Author)
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Bruchfeld, J
(Author)
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Cadiñanos Loidi, J
(Author)
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Caminero, JA
(Author)
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Carvalho, AC
(Author)
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Cebrian Gallardo, JJ
(Author)
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Charalampos,
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Danila, E
(Author)
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Davies Forsman, L
(Author)
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Denholm, J
(Author)
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Dheda, K
(Author)
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Diel, R
(Author)
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Diktanas, S
(Author)
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Dobler, C
(Author)
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Enwerem, M
(Author)
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Esposito, S
(Author)
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Escobar Salinas, N
(Author)
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Filippov, A
(Author)
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Formenti, B
(Author)
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García García, JM
(Author)
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Goletti, D
(Author)
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Gomez Rosso, R
(Author)
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Gualano, G
(Author)
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Isaakidis, P
(Author)
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Kaluzhenina, A
(Author)
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Koirala, S
(Author)
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Kuksa, L
(Author)
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Kunst, H
(Author)
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Li, Y
(Author)
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Magis Escurra, C
(Author)
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Manfrin, V
(Author)
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Manga, S
(Author)
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Manika, K
(Author)
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Marchese, V
(Author)
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Martínez Robles, E
(Author)
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Maryandyshev, A
(Author)
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Matteelli, A
(Author)
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Mariani, A
(Author)
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Mazza Stalder, J
(Author)
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Mello, F
(Author)
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Mendoza, L
(Author)
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Mesi, A
(Author)
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Miliauskas, S
(Author)
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Mustafa Hamdan, H
(Author)
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Ndjeka, N
(Author)
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Nieto Marcos, M
(Author)
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Ottenhoff, THM
(Author)
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Palmero, DJ
(Author)
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Palmieri, F
(Author)
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Papavasileiou, A
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Payen, MC
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Pontarelli, A
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Pretti Dalcolmo, M
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Quirós Fernandez, S
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Romero, R
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Rossato Silva, D
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Santos, AP
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Seaworth, B
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Sinitsyn, M
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Skrahina, A
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Solovic, I
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Spanevello, A
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Tadolini, M
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Torres, C
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Udwadia, Z
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van den Boom, M
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Volchenkov, GV
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Yedilbayev, A
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Zaleskis, R
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Zellweger, JP
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Journal
The Journal is awaiting validation by the Administrative Services.
Vol. 92
Pages: S15-S25
ISSN: 1201-9712
Other information
Authenticus ID: P-00R-S40
Resumo (PT):
Abstract (EN): The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Global Tuberculosis Network (GTN) experts. The core published documents and guidelines have been reviewed, including the recently published MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines. After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis (including whole genome sequencing and drug-susceptibility testing interpretations) and treatment (treatment design and management, TB in children) are discussed. Furthermore, the review comprehensively describes the latest information on contact tracing and LTBI management in MDR-TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities. (C) 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 11
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