Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Ferreira, J (Author) Other; Afonso, J (Author) Other; Carneiro, AL (Author) Other; Vila, I (Author) Other; Cunha, C (Author) Other; Roque, S (Author) Other; Silva, C (Author) Other; Mesquita, A (Author) Other; Cotter, J (Author) Other; Correia Neves, M (Author) Other; Mansilha A. (Author) FMUP; Longatto, A (Author) Other; Cunha, P (Author) Other

Journal

Title: Journal of Cardiovascular Development and Disease

Vol. 371

Final page: 271

ISSN: 2308-3425

Indexing

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Other information

Authenticus ID: P-00Y-TYV

DOI: 10.3390/jcdd10070271

Abstract (EN): The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to correlate them with cardiovascular risk factors, anthropometric measures and medication. An observational and prospective study was conducted, and 177 subjects were included. Peri-aortic adipose tissue had the highest density, while the subcutaneous adipose tissue had the lowest. The density of subcutaneous adipose tissue differs from the density of visceral (p = 0.00) and peri-aortic adipose tissue (p = 0.00). Smokers/ex-smokers had a lower area (p = 0.00) and density (p = 0.02) of subcutaneous adipose tissue. Multiple linear regression analysis showed that sex was a predictor of subcutaneous adipose tissue area (& beta; = -0.27, t = -3.12, p = 0.00) but smoking habits were not. After controlling for sex, we found that the association between smokers/ex-smokers and area of subcutaneous adipose tissue was lost, but the association with density persisted. Patients with hypertension had a higher visceral adipose tissue area, and this relationship was maintained even after adjusting for gender. Peri-aortic adipose tissue is similar to visceral and distinct from subcutaneous adipose tissue. Cardiovascular risk factors have different influences in distinct adipose compartments.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 17