Preoperative risk factors for early postoperative bleeding after Roux-en-Y gastric bypass surgery: a systematic review and meta-analysis

• Type: Another Publication in an International Scientific Journal
• Date: 2024

Authors

Santos-Sousa, H (Author) Other; Amorim-Cruz, F (Author) Other; Nogueiro, J (Author) Other; Silva, A (Author) Other; Amorim-Cruz, I (Author) Other; Ferreira-Santos, R (Author) Other; Bouca-Machado, R (Author) Other; Pereira, A (Author) Other; Resende, F (Author) Other; Costa-Pinho, A (Author) Other; Preto, J (Author) Other; Lima-da-Costa, E (Author) Other; Barbosa, E (Author) Other; Carneiro, S (Author) Other; Sousa-Pinto, B (Author) FMUP

Journal

The Journal is awaiting validation by the Administrative Services.

Title: LANGENBECKS ARCHIVES OF SURGERY

Vol. 409

ISSN: 1435-2443

Publisher: Springer

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-010-DZ8

DOI: 10.1007/s00423-024-03346-4

Abstract (EN): Purpose Although bariatric surgery is an effective intervention for obesity, it comes with risks such as early postoperative bleeding (EPB). Identifying preoperative risk factors for this complication can help patients' risk stratification and optimization. We performed a systematic review and meta-analysis to find predictors for early postoperative bleeding after Roux-en-Y gastric bypass (RYGB). Methods We conducted a systematic review, searching PubMed, Cochrane Library, and Web of Science until November 2023. We performed a random-effects meta-analysis to explore preoperative risk factors associated with early postoperative bleeding after RYGB. Sources of heterogeneity were explored by leave-one-out analyses. Results 23 studies were included, comprising 232,488 patients. Male gender (meta-analytical RR = 1.42, 95%CI = 1.21-1.66, I-2 = 18%, Q Cochran test p-value = 0.29) and revisional surgery (meta-analytical RR = 1.35, 95%CI = 1.12-1.62, I-2 = 22%, Q Cochran test p = 0.21) were associated with higher risk of EPB. On average, patients with EPB were older than the remainder (MD for the mean age = 2.82 years, 95%CI = 0.97-4.67, I-2 = 0.00%, Q Cochran test p = 0.46). Except for hypertension (meta-analytical RR = 1.33, 95%CI = 1.02-1.73, I-2 = 66%, Q Cochran test p < 0.0001), comorbidities were not associated with a higher risk of EPB. Conclusion Preoperative risk factors, including age, gender, hypertension, and revisional bariatric surgery, are associated with early postoperative bleeding after RYGB. Further primary studies, with higher methodological quality, are required to detail more risk factors.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9