Go to:
Logótipo
Comuta visibilidade da coluna esquerda
Você está em: Start > Publications > View > Metabolic signature biomarkers for predicting the recurrence of urological cancers
Publication

Publications

Metabolic signature biomarkers for predicting the recurrence of urological cancers

Title
Metabolic signature biomarkers for predicting the recurrence of urological cancers
Type
Article in International Scientific Journal
Year
2023-03-12
Journal
Title: Clinica Chimica ActaImported from Authenticus Search for Journal Publications
Vol. 549
ISSN: 0009-8981
Publisher: Elsevier
Indexing
Publicação em ISI Web of Knowledge ISI Web of Knowledge - 0 Citations
Publicação em Scopus Scopus - 0 Citations
Other information
Authenticus ID: P-00Z-2RA
Abstract (EN): A significant number of patients diagnosed with localized urological cancers experience relapse and disease progression after surgery. Hence, molecular markers for patient risk stratification are needed to improve the current management guidelines. This article critically reviews for the first time, to our knowledge, the promise of metabolomics-based approaches to identify metabolic signatures as candidate prognostic biomarkers to predict recurrences at the time of surgery in prostate cancer (PCa), bladder cancer (BCa), and renal cell carcinoma (RCC). Dysregulations in the levels of several tumoral, circulating, and excreted metabolites have been reported in PCa patients experiencing recurrence within 1.5 to 8 years of follow-up. The combination of these metabolic biomarkers with clinical parameters (e.g., pathological T stage, Gleason score) has shown great potential to improve the predictive ability of PCa recurrence. In contrast, predictive biomarkers of recurrence in BCa and RCC have been poorly explored. Overall, this review highlights the great potential of metabolomics in discovering prognostic biomarkers for a more accurate patient risk stratification in urological cancers.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 8
Documents
We could not find any documents associated to the publication.
Related Publications

Of the same authors

Update on 1-benzylpiperazine (BZP) party pills (2013)
Another Publication in an International Scientific Journal
Marcia Sa Monteiro; Maria de Lourdes Bastos; de Pinho, PG; Marcia Carvalho
Uncovering the Metabolic Footprint of New Psychoactive Substances by Metabolomics: A Systematic Review (2025)
Another Publication in an International Scientific Journal
Almeida, AS; de Pinho, PG; Fernando Remiao; Carla Fernandes
Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions (2021)
Another Publication in an International Scientific Journal
Araujo, AM; Felix Carvalho; de Pinho, PG; Carvalho, M
The Impact of Different Closures on the Flavor Composition of Wines during Bottle Aging (2021)
Another Publication in an International Scientific Journal
Furtado, I; Lopes, P; Oliveira, AS; Amaro, F; Maria de Lourdes Bastos; Cabral, M; de Pinho, PG; Pinto, J
The hallucinogenic world of tryptamines: an updated review (2015)
Another Publication in an International Scientific Journal
Ana Margarida Araujo; Felix Carvalho; Maria de Lourdes Bastos; Guedes de Pinho, P; Marcia Carvalho

See all (251)

Of the same journal

Current analytical strategies for C-reactive protein quantification in blood (2013)
Another Publication in an International Scientific Journal
Manuel Algarra; Diana Gomes; Joaquim C G E Esteves da Silva
Obesity and normal C-reactive protein: Diminished cardiovascular risk? (2005)
Other Publications
guimaraes, jt; santos, ac; candeias, j; barros, h
Cardiac markers in ambulatory heart failure patients-effect of optimized therapy (2005)
Other Publications
guimaraes, jt; osorio, e; frioes, f; bettencourt, p; machado-vaz, m
Variations in the GLA gene correlate with globotriaosylceramide and globotriaosylsphingosine analog levels in urine and plasma (2015)
Article in International Scientific Journal
Ferreira, S; Auray Blais, C; Boutin, M; Lavoie, P; José Pedro Nunes; Martins, E; Garman, S; João Paulo Oliveira

See all (19)

Recommend this page Top
Copyright 1996-2025 © Faculdade de Direito da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z
Page created on: 2025-07-26 at 02:27:34 | Privacy Policy | Personal Data Protection Policy | Whistleblowing