New Perspective for Drug-Drug Interaction in Perioperative Period

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Silva, A (Author) Other; Costa, B (Author) Other; Castro, I (Author) Other; J Mourão (Author) FMUP; Nuno Vale (Author) FMUP

Journal

Title: Journal of Clinical Medicine

Vol. 12 No. Article 2338

Final page: 4810

ISSN: 2077-0383

Publisher: MDPI

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 2 Citations

Other information

Authenticus ID: P-00Y-P2V

DOI: 10.3390/jcm12144810

Abstract (EN): In this review, we aim to discuss current information on drug interactions in the perioperative period. During this period, patients receive several drugs that may interact with each other and affect the efficacy and safety of the treatment. There are three types of drug interactions: pharmacodynamic, pharmacokinetic, and pharmaceutical. It is important to recognize that drug interactions may increase the toxicity of the drug or reduce its efficacy, increasing the risk of complications in the perioperative period. This review describes the most commonly used perioperative drugs approved by the FDA and some of the described interactions between them. Thoroughly reviewing a patient's medication list and identifying potential interactions are essential steps in minimizing risks. Additionally, vigilant monitoring of patients during and after surgery plays a pivotal role in early detection of any signs of drug interactions. This article emphasizes the significance of addressing DDIs in the perioperative period to ensure patient well-being and advocates for the implementation of careful monitoring protocols to promptly identify and manage potential interactions.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 18