Electrochemical study of proton ionisation, copper(II) complexation and surfactant properties of piperazine-N-N '-bis[2-hydroxypropanesulfonic acid] pH buffer - Comparison with other N-substituted aminosulfonic acids pH buffers

• Type: Article in International Scientific Journal
• Date: 1998

Authors

Vasconcelos, MTSD (Author) Other; Marisa M R Almeida (Author) Other

Journal

Title: Analytica Chimica Acta

Vol. 369

Pages: 115-122

ISSN: 0003-2670

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 13 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-001-7A4

DOI: 10.1016/s0003-2670(98)00239-6

Abstract (EN): The surface active behaviour of the piperazine-N-N'-bis[2-hydroxypropanesulfonic acid] (POPSO) and its capability to bind copper(II) were investigated at 25 degrees C and 0.5 mol l(-1) ionic strength. For acid dissociation and copper(II)-buffer complexation determinations, ion selective electrode potentiometric titration data (pH or pH plus pCu measurements) were evaluated with the help of SUPERQUAD computational program. The buffer concentration influenced markedly the results. At 10 mmol l(-1) buffer, pK(a1) = 7.69 and pK(a2) = 8.20 were obtained. At 2.0 mmol l(-1), pK(a2) = 7.92 and insolubility of the buffer at pH less than or equal to 7.0 prevented the determination of pK(a1). Too low buffer power of the solution prevented the determination of the pK(a2) value at 0.8 mmol l(-1). At that POPSO concentration, the following Cu(II)-POPSO stability constants (log beta(ab), corresponding to the equilibrium: aCU(2+) + bL(2-) <-> [MaLb](2a-2b); H2L = POPSO) were obtained: beta(11) = 4.1, beta(12) = 8.1, beta(13) = 12 beta(14) = 16, beta(15) = 19, beta(16) = 23 The values of beta(ab) (and the statistical quality of the fit) decreased when the buffer concentration increased (e.g., log beta(13) = 9.6 at 10 mmol l(-1) POPSO). Aggregation of molecules of POPSO may be the cause of this behaviour. Demonstration of a marked surface active behaviour of 10 mmol 1-' POPSO solution was obtained by alternating current polarography. A conditional stability constant of Cu(II)-buffer at 10 mmol 1-' POPSO concentration and pH = 8.0, was also determined by the Scatchard method: log K = 5.7 (/Cu(II)/bound/ /buffer/(total): 0.088-0.19). The POPSO properties are compared with those of other similar zwitterionic compounds previously studied by us: N-[2-hydroxyethyl]piperazine-N'-[2-ethanesulfonic acid] (HEPES), N-[2-hydroxyethyl]piperazine-N'-[2-hydroxpropanesulfonic acid] (HEPPSO), 3-[N,N-bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid (DIPSO) and piperazine-N,N'-bis[2-ethanesulfonic acid] (PIPES).

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8