Challenging the concept of "risk of malignancy" in cytology

• Type: Another Publication in an International Scientific Journal
• Date: 2023

Authors

Nikas, IP (Author) Other; da Silva, RS (Author) Other; Sousa Pinto, B (Author) FMUP; Fernando Schmitt (Author) FMUP

Journal

Title: Cancer Cytopathology

ISSN: 1934-662X

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 3 Citations

Scopus - 3 Citations

Other information

Authenticus ID: P-00Z-H9T

DOI: 10.1002/cncy.22787

Abstract (EN): Several standardized systems for nongynecological cytopathology have been published following the successful implementation of The Bethesda System for Reporting Cervical Cytology. Each of these systems comprises a set of reporting categories accompanied by a risk of malignancy. However, in most cases, these risk of malignancy estimates have not been based on high-quality evidence and often may not be consider proper risks (because they have been estimated based on cross-sectional studies). This commentary discusses the problems related to the data used to generate these risks. To make nongynecological cytopathology reporting more evidence-based, large-scale prospective cohort studies and randomized trials, in addition to high-quality systematic reviews and meta-analyses, should be performed.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5