Hyperfunctioning papillary thyroid carcinoma - a case report and literature review

• Type: Another Publication in an International Scientific Journal
• Date: 2023

Authors

Pereira-Macedo, J (Author) Other; Freire, B (Author) Other; Macedo-Oliveira, C (Author) Other; Mendes, J (Author) Other; Carvalho, M (Author) Other; Rocha-Neves, J (Author) FMUP; Fonseca, S (Author) Other; Vinagreiro, M (Author) Other; Lemos, R (Author) Other; Silva, N (Author) Other; Sampaio, F (Author) Other

Journal

Title: Acta Chirurgica Belgica

Pages: 1-6

ISSN: 0001-5458

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 0 Citations

Other information

Authenticus ID: P-00Y-BAB

DOI: 10.1080/00015458.2023.2210699

Abstract (EN): Background Malignant hyperfunctioning thyroid nodules are rare and more likely to occur in follicular cancer types rather than papillary variants. The authors present a case of a papillary thyroid carcinoma associated with a hyperfunctioning nodule. Methods A single adult patient submitted to total thyroidectomy with the presence of thyroid carcinoma within hyperfunctioning nodules was selected. Additionally, brief literature was conducted. Results An asymptomatic 58-year-old male was subjected to routine blood analysis and a TSH level of <0.003 mIU/L was found. Ultrasonography revealed a 21 mm solid, hypoechoic, and heterogenous nodule with microcalcifications in the right lobe. A fine needle aspiration guided by ultrasound resulted in a follicular lesion of undetermined significance. A Tc-99m thyroid scintigram was followed and identified a right-sided hyperfunctioning nodule. Another cytology was performed and a papillary thyroid carcinoma was derived as a result. The patient underwent a total thyroidectomy. Postoperative histology confirmed the diagnosis and a tumor-free margin with no vascular or capsular invasions. Conclusion Hyperfunctioning malignant nodules are a rare association, although a careful approach should be led since major clinical implications arise. Selective fine needle aspiration in all suspicious & GE;1 cm nodules should be considered.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 6