R2CHA2DS2-VA Predictsthe Cardiovascular Risk after Carotid Endarterectomy

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Quesado, J (Author) Other; Dias, L (Author) Other; Pereira Macedo, J (Author) Other; Duarte Gamas, L (Author) Other; Khairy, A (Author) Other; Pinheiro, M (Author) Other; Reis, P (Author) Other; Andrade, JP (Author) FMUP; Rocha Nerves, J (Author) FMUP; Marreiros, A (Author) Other

Journal

Title: Annals of Vascular Surgery

Vol. 94

Pages: 205-212

ISSN: 0890-5096

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00X-ZDS

DOI: 10.1016/j.avsg.2023.02.016

Abstract (EN): Background: R2CHA2DS2-VA score has been used to predict short and long-term outcomes in many cardiovascular diseases. This study aims to validate the R2CHA2DS2-VA score as a long-term major adverse cardiovascular events (MACE) predictor after carotid endarterectomy (CEA). Secondary outcomes were also assessed regarding the incidence of all-cause mortality, acute myocardial infarction (AMI), major adverse limb events (MALE), and acute heart failure (AHF).Methods: From January 2012 to December 2021, patients (n 1/4 205) from a Portuguese tertiary care and referral center that underwent CEA with regional anesthesia (RA) for carotid stenosis (CS) were selected from a previously collected prospective database, and a posthoc analysis was performed. Demographics and comorbidities were registered. Clinical adverse events were assessed 30 days after the procedure and in the subsequent long-term surveillance period. Statistical analysis was performed by the Kaplan-Meier method and Cox proportional hazards regression.Results: Of the patients enrolled, 78.5% were males with a mean age of 70.44 & PLUSMN; 8.9 years. Higher scores of R2CHA2DS2-VA were associated with long-term MACE (adjusted hazard ratio (aHR) 1.390; 95% confidence interval (CI) 1.173-1.647); and mortality (aHR 1.295; 95% CI 1.08-1.545). Conclusions: This study demonstrated the potential of the R2CHA2DS2-VA score to predict long-term outcomes, such as AMI, AHF, MACE, and all-cause mortality, in a population of pa-tients submitted to carotid endarterectomy.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8