Controlling the depth of anesthesia by a novel positive control strategy

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Nogueira, FN (Author) Other; Mendonca, T (Author) FCUP; Rocha, P (Author) FEUP

Journal

Title: Computer Methods and Programs in Biomedicine

Vol. 114 No. 3

Pages: E87-E97

ISSN: 0169-2607

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 23 Citations

ISI Web of Science

Scopus - 30 Citations

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

Other information

Authenticus ID: P-009-A2N

DOI: 10.1016/j.cmpb.2013.12.016

Abstract (EN): In this paper a positive control law is designed for multi-input positive systems that ensures asymptotic tracking of a desired output reference value. This control law can be viewed as a generalization of another one proposed in the literature for the control of the total mass in SISO compartmental systems, but is suitable for a wider class of positive systems. The controller proposed here is applied to the control of the depth of anesthesia (DoA), by means of the administration of propofol and remifentanil, when using a parameter parsimonious Wiener model recently introduced in the literature. Its performance is illustrated by realistic simulations.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 11