Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Sousa Pinto, B (Author) FMUP; Louis, G (Author) Other; Rodrigues, J (Author) Other; Giuliano, AFM (Author) Other; Baiardini, I (Author) Other; Braido, F (Author) Other; Czarlewski, W (Author) Other; Bedbrook, A (Author) Other; Haahtela, T (Author) Other; Valiulis, A (Author) Other; Brussino, L (Author) Other; Cecchi, L (Author) Other; Cruz, AA (Author) Other; Gemicioglu, B (Author) Other; Fokkens, WJ (Author) Other; Ivancevich, JC (Author) Other; Klimek, L (Author) Other; Kraxner, H (Author) Other; Kuna, P (Author) Other; Kupczyk, M (Author) Other; Kvedariene, V (Author) Other; Larenas Linnemann, D (Author) Other; Louis, R (Author) Other; Nadif, R (Author) Other; Niedoszytko, M (Author) Other; Okamoto, Y (Author) Other; Ollert, M (Author) Other; Papadopoulos, NG (Author) Other; Patella, V (Author) Other; Pawankar, R (Author) Other; Pham Thi, N (Author) Other; Pfaar, O (Author) Other; Regateiro, FS (Author) Other; Roche, N (Author) Other; Rouadi, PW (Author) Other; Samolinski, B (Author) Other; Sastre, J (Author) Other; Savoure, M (Author) Other; Scichilone, N (Author) Other; Sheikh, A (Author) Other; Taborda Barata, L (Author) Other; ToPPila Salmi, S (Author) Other; Yorgancioglu, A (Author) Other; Zidarn, M (Author) Other; Anto, JM (Author) Other; Zuberbier, T (Author) Other; Canonica, GW (Author) Other; Ventura, MT (Author) Other; Fonseca, J (Author) FMUP; Petre, B (Author) Other; Bousquet, J (Author) Other

Journal

Title: Journal of Allergy and Clinical Immunology: In Practice

Vol. 11

Initial page: 3742

ISSN: 2213-2198

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 7 Citations

Scopus - 7 Citations

Other information

Authenticus ID: P-00Y-W0P

DOI: 10.1016/j.jaip.2023.08.006

Abstract (EN): BACKGROUND: EQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control. OBJECTIVE: To assess the association between rhinitis or asthma control and the different EQ-5D-5L domains using data from the MASK-air mHealth app. METHODS: In this cross-sectional study, we assessed data from all MASK-air users (2015-2021; 24 countries). For the levels of each EQ-5D-5L domain, we assessed rhinitis and asthma visual analog scales (VASs) and the combined symptom-medication score (CSMS). We built ordinal multivariable models assessing the adjusted association between VAS/CSMS values and the levels of each EQ-5D-5L domain. Finally, we compared EQ-5D-5L data from users with rhinitis and self-reported asthma with data from users with rhinitis alone. RESULTS: We assessed 5354 days from 3092 users. We observed an association between worse control of rhinitis or asthma (higher VASs and CSMS) and worse EQ-5D-5L levels. In multivariable models, all VASs and the CSMS were associated with higher levels of pain/discomfort and daily activities. For anxiety/depression, the association was mostly observed for rhinitis-related tools (VAS nose, VAS global, and CSMS), although the presence of self-reported asthma was also associated with worse anxiety/depression. Worse mobility (walking around) was particularly associated with VAS asthma and with the presence of asthma.CONCLUSIONS: A worse rhinitis control and a worse asthma control are associated with higher EQ-5D-5L levels, particularly regarding pain/discomfort and activity impairment. Worse rhinitis control is associated with worse anxiety/depression, and poor asthma control with worse mobility. (c) 2023 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:3742-51)

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 19