Evaluating the ability of an artificial-intelligence cloud-based platform designed to provide information prior to locoregional therapy for breast cancer in improving patient's satisfaction with therapy: The CINDERELLA trial

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Kaidar Person, O (Author) Other; Antunes, M (Author) Other; Jaime S Cardoso (Author) FEUP; Ciani, O (Author) Other; Cruz, H (Author) Other; Di Micco, R (Author) Other; Gentilini, D (Author) Other; Gonçalves, T (Author) Other; Gouveia, P (Author) Other; Heil, J (Author) Other; Kabata, P (Author) Other; Lopes, D (Author) Other; Martinho, M (Author) Other; Martins, H (Author) Other; Mavioso, C (Author) Other; Mika, M (Author) Other; Montenegro, H (Author) Other; Oliveira, HP (Author) FCUP; Pfob, A (Author) Other; Rotmensz, N (Author) Other; Schinköthe, T (Author) Other; Silva, G (Author) Other; Tarricone, R (Author) Other; Cardoso, M (Author) Other

Journal

Title: PLoS ONE

Vol. 18 No. 2, e0279344

ISSN: 1932-6203

Publisher: Public Library of Science

Indexing

ISI Web of Knowledge - 7 Citations

Scopus - 8 Citations

Other information

Authenticus ID: P-00Y-T69

DOI: 10.1371/journal.pone.0289365

Abstract (EN): BackgroundBreast cancer therapy improved significantly, allowing for different surgical approaches for the same disease stage, therefore offering patients different aesthetic outcomes with similar locoregional control. The purpose of the CINDERELLA trial is to evaluate an artificial-intelligence (AI) cloud-based platform (CINDERELLA platform) vs the standard approach for patient education prior to therapy. MethodsA prospective randomized international multicentre trial comparing two methods for patient education prior to therapy. After institutional ethics approval and a written informed consent, patients planned for locoregional treatment will be randomized to the intervention (CINDERELLA platform) or controls. The patients in the intervention arm will use the newly designed web-application (CINDERELLA platform, CINDERELLA APProach) to access the information related to surgery and/or radiotherapy. Using an AI system, the platform will provide the patient with a picture of her own aesthetic outcome resulting from the surgical procedure she chooses, and an objective evaluation of this aesthetic outcome (e.g., good/fair). The control group will have access to the standard approach. The primary objectives of the trial will be i) to examine the differences between the treatment arms with regards to patients' pre-treatment expectations and the final aesthetic outcomes and ii) in the experimental arm only, the agreement of the pre-treatment AI-evaluation (output) and patient's post-therapy self-evaluation. DiscussionThe project aims to develop an easy-to-use cost-effective AI-powered tool that improves shared decision-making processes. We assume that the CINDERELLA APProach will lead to higher satisfaction, better psychosocial status, and wellbeing of breast cancer patients, and reduce the need for additional surgeries to improve aesthetic outcome.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 12