Synthesis of Iminosugars from Tetroses

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Sousa, CE (Author) Other; Mendes, RR (Author) Other; Costa, FT (Author) Other; Duarte, VCM (Author) Other; Fortes, AG (Author) Other; Alves, MJ (Author) Other

Journal

The Journal is awaiting validation by the Administrative Services.

Title: CURRENT ORGANIC SYNTHESIS

Vol. 11

Pages: 182-203

ISSN: 1570-1794

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 6 Citations

Other information

Authenticus ID: P-009-SEX

DOI: 10.2174/15701794113106660074

Abstract (EN): Iminosugars continue receiving a great deal of attention from chemists and biochemists for their potential as pharmaceutics. This is a comprehensive review of the methods found in the literature for the synthesis of piperidine, pyrrolidine, indolizidine, and pirrolizidine iminosugars, starting from D/L-erythrose and D/L-threose carbon chains (tetroses). This review shows the crescent popularity of small molecules to build up iminosugar molecules. Methodologies described herein utilize inexpensive commercial materials. The synthesis of the four tetroses is included referring old and modern methodologies.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 22