A review of migraine genetics: gathering genomic and transcriptomic factors

• Type: Another Publication in an International Scientific Journal
• Date: 2021

Authors

Dias, A (Author) Other; Mariz, T (Author) Other; Sousa, A (Author) Other; Carolina Lemos (Author) ICBAS; Alves Ferreira, M (Author) Other

Journal

Title: Human Genetics

Vol. 141

Pages: 1-14

ISSN: 0340-6717

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00V-KRF

DOI: 10.1007/s00439-021-02389-7

Abstract (EN): Migraine is a common and complex neurologic disorder that affects approximately 15-18% of the general population. Although the cause of migraine is unknown, some genetic studies have focused on unravelling rare and common variants underlying the pathophysiological mechanisms of this disorder. This review covers the advances in the last decade on migraine genetics, throughout the history of genetic methodologies used, including recent application of next-generation sequencing techniques. A thorough review of the literature interweaves the genomic and transcriptomic factors that will allow a better understanding of the mechanisms underlying migraine pathophysiology, concluding with the clinical utility landscape of genetic information and future consideration to creating a new frontier toward advancing the field of personalized medicine.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 14