Does Multicomponent Physical Exercise Training Work for Dementia? Exploring the Effects on Cognition, Neuropsychiatric Symptoms, and Quality of Life

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Borges Machado, F (Author) Other; Teixeira, L (Author) ICBAS; Maria Carvalho (Author) FADEUP; Ribeiro, O (Author) Other

Journal

Title: Journal of Geriatric Psychiatry and Neurology

Vol. 36

Pages: 376-385

ISSN: 0891-9887

Publisher: SAGE

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 1 Citation

Other information

Authenticus ID: P-00X-Q86

DOI: 10.1177/08919887221149152

Abstract (EN): Objective To explore the effects of a multicomponent training (MT) physical exercise intervention in the cognitive function, neuropsychiatric symptoms, and quality of life of older adults with major neurocognitive disorder (NCD). Methods Quasi-experimental controlled trial. Thirty-six individuals (25 female) were equally distributed to an exercise group (aged 74.33 +/- 5.87 years) or a control group (aged 81.83 +/- 6.18 years). The Alzheimer's Disease Assessment Scale - Cognitive (ADAS-Cog), the Neuropsychiatric Inventory (NPI) and the Quality of Life - Alzheimer's Disease (QoL-AD) tests were performed before and after the intervention. Results There was no clear interaction effect factor of intervention on ADAS-Cog (B = 1.33, 95% CI: -2.61 - 5.28, P = .513), NPI (B = -8.35, 95% CI: -18.48 - 1.72, P = .115), and QoL-AD (B = 2.87, 95% CI: .01 - 5.73, P = .058). Conclusions The 6-month MT physical exercise intervention did not present evidence of slowing down cognitive decline neither improving neuropsychiatric symptomatology, and quality of life of older adults with major NCD. Future studies with larger samples are needed to better understand the impact of physical exercise interventions using MT methodology on specific cognitive abilities, neuropsychiatric symptoms, and quality of life domains.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10