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European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity

Title
European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity
Type
Article in International Scientific Journal
Year
2020
Authors
Pasquali, R
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Casanueva, F
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Haluzik, M
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van Hulsteijn, L
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Ledoux, S
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Monteiro, M
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Salvador, J
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Santini, F
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Toplak, H
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Dekkers, OM
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Journal
Vol. 182
Pages: G1-G32
ISSN: 0804-4643
Publisher: BioScientifica Ltd.
Other information
Authenticus ID: P-00R-GJ4
Abstract (EN): Obesity is an emerging condition, with a prevalence of -20%. Although the simple measurement of BMI is likely a simplistic approach to obesity, BMI is easily calculated, and there are currently no data showing that more sophisticated methods are more useful to guide the endocrine work-up in obesity. An increased BMI leads to a number of hormonal changes. Additionally, concomitant hormonal diseases can be present in obesity and have to be properly diagnosed - which in turn might be more difficult due to alterations caused by body fatness itself. The present European Society of Endocrinology Clinical Guideline on the Endocrine Work-up in Obesity acknowledges the increased prevalence of many endocrine conditions in obesity. It is recommended to test all patients with obesity for thyroid function, given the high prevalence of hypothyroidism in obesity. For hypercortisolism, male hypogonadism and female gonadal dysfunction, hormonal testing is only recommended if case of clinical suspicion of an underlying endocrine disorder. The guideline underlines that weight loss in obesity should be emphasized as key to restoration of hormonal imbalances and that treatment and that the effect of treating endocrine disorders on weight loss is only modest.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 32
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