RNA methyltransferases in plants: Breakthroughs in function and evolution

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Ferraz, R (Author) Other; Coimbra, S (Author) FCUP; Correia, S (Author) Other; Canhoto, J (Author) Other

Journal

Title: Plant Physiology and Biochemistry

Vol. 194

Pages: 449-460

ISSN: 0981-9428

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus

Other information

Authenticus ID: P-00X-PQR

DOI: 10.1016/j.plaphy.2022.12.001

Abstract (EN): Each day it is becoming increasingly difficult not to notice the completely new, fast growing, extremely intricate and challenging world of epitranscriptomics as the understanding of RNA methylation is expanding at a hasty rate. Writers (methyltransferases), erasers (demethylases) and readers (RNA-binding proteins) are responsible for adding, removing and recognising methyl groups on RNA, respectively. Several methyltransferases identified in plants are now being investigated and recent studies have shown a connection between RNA-methyltransferases (RNA-MTases) and stress and development processes. However, compared to their animal and bacteria coun-terparts, the understanding of RNA methyltransferases is still incipient, particularly those located in organelles. Comparative and systematic analyses allowed the tracing of the evolution of these enzymes suggesting the ex-istence of several methyltransferases yet to be characterised. This review outlines the functions of plant nuclear and organellar RNA-MTases in plant development and stress responses and the comparative and evolutionary discoveries made on RNA-MTases across kingdoms.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 12