Go to:
Logótipo
Comuta visibilidade da coluna esquerda
Você está em: Start > Publications > View > Nanomedicine Interventions in Clinical Trials for the Treatment of Metastatic Breast Cancer
Publication

Publications

Nanomedicine Interventions in Clinical Trials for the Treatment of Metastatic Breast Cancer

Title
Nanomedicine Interventions in Clinical Trials for the Treatment of Metastatic Breast Cancer
Type
Another Publication in an International Scientific Journal
Year
2021
Authors
Moreira, R
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Granja, A
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Pinheiro, M
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Salette Reis
(Author)
FFUP
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page View ORCID page
Journal
Title: Applied SciencesImported from Authenticus Search for Journal Publications
Vol. 11
Pages: 1-13
Publisher: MDPI
Indexing
Publicação em ISI Web of Knowledge ISI Web of Knowledge - 0 Citations
Publicação em Scopus Scopus - 0 Citations
Other information
Authenticus ID: P-00T-FDK
Abstract (EN): Breast cancer was responsible for the deaths of 626,679 women in 2018. After decades of research, the mortality rates remain high. While the barrier of selectively killing tumor cells is not yet overcome, the search for targeted therapeutics continues. The use of nanomedicine in cancer treatment has opened up new possibilities for more precise drug-delivery systems. This review aimed to gather information and analyze recent clinical trials evaluating the therapeutic effects of nanoparticles in the treatment of metastatic breast cancer. To accomplish this, the clinicaltrials.gov database was consulted, and after employing specific exclusion criteria, 11 clinical trials were selected. Nanoparticle albumin-stabilized paclitaxel was evaluated in ten clinical trials and paclitaxel-incorporating polymeric micelles were assessed in one clinical trial. Overall, this review confirmed a clinical benefit in the use of nanoparticle albumin-stabilized paclitaxel for the treatment of breast cancer, with reduced toxicity when compared to first-line treatments. Three studies did not meet the primary endpoint, however, and so the authors advised further evaluations. Although the use of nanomedicine is revolutionizing the cancer field, to integrate this regimen into generalized clinical treatment, additional clinical trials must be performed to achieve a favorable safety and efficacy profile.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 13
Documents
We could not find any documents associated to the publication.
Related Publications

Of the same journal

Wound Dressing Materials: Bridging Material Science and Clinical Practice (2025)
Another Publication in an International Scientific Journal
Ferraz, MP
Viscoelasticity: Mathematical Modelling, Numerical Simulations, and Experimental Work (2023)
Another Publication in an International Scientific Journal
Ferras, LL; Afonso, AM
Thermal conductivity of nanofluids: A review on prediction models, controversies and challenges (2021)
Another Publication in an International Scientific Journal
Gonçalves, I; Souza, R; Coutinho, G; Miranda, JM; Moita, A; Pereira, JE; Moreira, A; Lima, R
Theories and Analysis of Functionally Graded Beams (2021)
Another Publication in an International Scientific Journal
J. N. Reddy; Eugenio Ruocco; Jose A. Loya; Ana M. A. Neves
The Yeast-Based Probiotic Encapsulation Scenario: A Systematic Review and Meta-Analysis (2024)
Another Publication in an International Scientific Journal
Oliveira, WD; de Brito, LP; de Souza, EAG; Lopes, IL; de Oliveira, CA; Calaça, PRD; M B P P Oliveira; Costa, ED

See all (285)

Recommend this page Top
Copyright 1996-2025 © Faculdade de Direito da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z
Page created on: 2025-07-10 at 00:01:19 | Privacy Policy | Personal Data Protection Policy | Whistleblowing