Molecular modifications, biological activities, and applications of chitosan and derivatives: A recent update

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Lima, R (Author) Other; Carla Fernandes (Author) FFUP; Pinto, MMM (Author) Other

Journal

Title: Chirality

Vol. 34

Pages: 1166-1190

ISSN: 0899-0042

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00W-Q0V

DOI: 10.1002/chir.23477

Abstract (EN): Polysaccharides arouse great interest due to their structure and unique properties, such as biocompatibility, biodegradability, and absence of toxicity. Polysaccharides from marine sources are particularly useful due to the wide variety of applications and biological activities. Chitosan, a deacetylated derivative of chitin, is an example of an interesting bioactive marine-derived polysaccharide. Moreover, a wide variety of chemical modifications and conjugation of chitosan with other bioactive molecules are responsible for improvements in physicochemical properties and biological activities, expanding the range of applications. An overview of the synthetic approaches for preparing chitosan, chitosan derivatives, and conjugates is described and discussed. A recent update of the biological activities and applications in different research fields, mainly focused on the last 5 years, is presented, highlighting current trends.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 25