Systemic inflammatory indices derived from complete blood count in assessment of future cardiovascular risk in preeclampsia

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Pereira Da Silva Oliveira, A (Author) Other; Andreea Rechitean, A (Author) Other; Ana Carolina Santos, M (Author) Other; Andreia Matos, M (Author) Other; Ana Portelinha, P (Author) Other; Maria Jose Areias, M (Author) Other; Manuel Bicho, M (Author) Other; Rebelo, I (Author) FFUP; Maria Clara Bicho, M (Author) Other

Journal

Title: European Journal of Preventive Cardiology

Vol. 29

ISSN: 2047-4873

Publisher: SAGE

Other information

Authenticus ID: P-00Y-4WW

DOI: 10.1093/eurjpc/zwac056.159

Abstract (EN): <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Funding Acknowledgements</jats:title> <jats:p>Type of funding sources: Foundation. Main funding source(s): FCT, Portugal</jats:p> <jats:p>Systemic inflammatory parameters derived from complete blood count (CBC) might present a good potential and a cheap method in assessment the risk for the development of cardiovascular related diseases.</jats:p> <jats:p>The aim of this research is to retrospectively evaluate the interplay of CBC derived indexes with other inflammatory parameters in women with arterial hypertension after a history of preeclampsia.</jats:p> <jats:p>Clinical and laboratory data were collected and analysed in 170 previously pregnant women (n=170) with a mean age of 35 years (s= 5.477 years) and the average BMI value equal to 26.4 kg/m2 (s= 4.57 kg/m2), and the follow-up period was 10 years after pregnancy.</jats:p> <jats:p>The majority of women who currently present hypertension (52.9%), were diagnosed previously with preeclampsia (97.8%, p=0.000). Compared to the non preeclamptic population, theese women present differences in BMI (p=0.002), waist circumference (p=0.000), hip circumference (p=0.045, M. Whitney), waist /hip ratio (p=0.001), granulocyte (p=0.037), Granulocyte X platelet/lymphocyte ratio (p=0.034), neutrophil/lymphocyte ratio (p=0.034, M. Whitney), ApoB (p=0.023) and NOX concentration (p= 0.033).</jats:p> <jats:p>Prior preeclamptic women were associated with a higher risk of developing hypertension. Anthropometric data suggests that BMI, waist circumference, hip/waist ratio and CBC derived inflammatory indeces are parameters that can aid in prognosis of future hypertension in women.</jats:p> </jats:sec>

Language: English

Type (Professor's evaluation): Scientific