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Fourier transform infrared (FT-IR) spectroscopy typing: a real-time analysis of an outbreak by carbapenem-resistantKlebsiella pneumoniae

Title
Fourier transform infrared (FT-IR) spectroscopy typing: a real-time analysis of an outbreak by carbapenem-resistantKlebsiella pneumoniae
Type
Article in International Scientific Journal
Year
2020
Authors
Silva, L
(Author)
Other
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Rodrigues, C
(Author)
Other
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Lira, A
(Author)
Other
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Leao, M
(Author)
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Mota, M
(Author)
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Lopes, P
(Author)
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Novais, A
(Author)
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Luisa Peixe
(Author)
FFUP
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Journal
Vol. 39
Pages: 2471-2475
ISSN: 0934-9723
Publisher: Springer Nature
Indexing
Other information
Authenticus ID: P-00S-F18
Abstract (EN): The spread of multidrug-resistant (MDR)Klebsiella pneumoniaein the nosocomial setting represents a big challenge to infection control teams. We have recently developed a simple spectroscopic-based method with excellent accuracy, turnaround time and cost-effectiveness (Rodrigues et al. mSystems 2020) for bacterial typing. Here, we applied our method in a real clinical context to support early identification of an outbreak involving KPC-3-producingK. pneumoniaeST147 isolates. Our results further support that attenuated total reflectance Fourier transform infrared (FT-IR) spectroscopy can provide enough information to support early and adequate infection control measures and therapeutic choices in the context of nosocomial outbreaks and hospital surveillance.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 5
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