Analytical Methods for Determination of BPA Released from Dental Resin Composites and Related Materials: A Systematic Review

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Lopes Rocha, L (Author) Other; Hernandez, C (Author) Other; Goncalves, V (Author) Other; Pinho, T (Author) Other; M E Tiritan (Author) FFUP

Journal

Title: Critical Reviews in Analytical Chemistry

Pages: 1-16

ISSN: 1040-8347

Publisher: Taylor & Francis

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 4 Citations

Other information

Authenticus ID: P-00W-VDS

DOI: 10.1080/10408347.2022.2093097

Abstract (EN): Knowing the impacts of bisphenol A (BPA) on human health, this systematic review aimed to gather the analytical methods for the quantification of BPA release of BPA in dental materials in in vitro and in vivo (biological fluids) studies. A brief critical discussion of the impacts of BPA on human health and the possible association with BPA in dental materials was also presented. The research was carried out by three independent researchers, (according to PRISMA guidelines) in PUBMED and SCOPUS databases, by searching for specific keywords and articles published between January 2011 and February 2022. Seventeen articles met the eligibility criteria and were included in this systematic review: 10 in vitro and 7 in vivo. In in vitro studies, the highest amounts of BPA released were from flowable to conventional resins, followed by resin-modified glass ionomer. In contrast, the smallest amount was released from BPA-free composites and CAD-CAM blocks. Regarding in vivo studies, a higher concentration of BPA were found in saliva than urine or blood. The best analytical method for trace quantifying BPA is LC-MS/MS (Liquid Chromatography with Tandem Mass Spectrometry) due to its selectivity, low quantification limits, and the unequivocal identification. However, further studies are required to develop faster and more sensitive methods, in order to obtain more reliable results.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 16