The Highly Focalized Thermotherapy in the treatment of solid tumors: Temperature monitoring using thermography

• Type: Article in International Scientific Journal
• Date: 2012

Authors

Portela A. (Author) Other; Vasconcelos M. (Author) Other; Silva A. (Author) FEUP; Gabriel J. (Author) Other; Cavalheiro J. (Author) Other

Journal

Title: Thermology International

Vol. 22

Pages: 95-98

ISSN: 1560-604X

Publisher: European Association of Thermology

Indexing

Scopus - 0 Citations

Other information

Authenticus ID: P-00W-01Z

Abstract (EN): The use of hyperthermia in the tumor treatment is based on the well-established concept that heat has selective lethal effects on tumor tissues. A new hyperthermia technique, the Highly Focalized Thermotherapy (HFT), was developed in an attempt to localize the heat in the tumor. The aim of the present study was to evaluate the capability of monitoring the temperature variation by using the HFT in a melanoma mice model, through thermography. B16F10 melanoma mice (C56BL6) were injected with a Ferrimagnetic Cement and exposed to a high frequency magnetic field to generate heat within the tumor. The animal body temperature was monitored through a thermal camera FLIR A325, after removing the fur in the area of the tumor. Through thermography, the skin temperature was assessed and logged its maximum value. The HFT application in the melanoma mice model resulted in a temperature increase in the tumor. Comparing the initial tumor temperature with the tumor treatment temperature, there was an increase of 5-6 °C in the first 5-10 minutes, whereas the body temperature showed only a limited increase (2-3 °C). In this superficial melanoma model, the animal's temperature can be monitored using a thermographic camera. It is possible to measure the temperature variation, simultaneously, in the whole body and in the tumor, during the treatment, preventing unwanted heat effects in other tissues.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3