Review of 175 Cases of Tuberculosis Infections Affecting the Urogenital System

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Dias, N (Author) Other; Pina Vaz, T (Author) Other; Abreu Mendes, P (Author) Other; Azeredo Costa, T (Author) Other; Rodrigues Pereira, P (Author) Other; Carlos Silva (Author) FMUP; Botelho, F (Author) Other

Journal

The Journal is awaiting validation by the Administrative Services.

Title: Turkish Journal of Urology

Vol. 48

Pages: 440-445

ISSN: 2149-3235

Indexing

Scopus - 440 Citations

Other information

Authenticus ID: P-00X-GFD

DOI: 10.5152/tud.2022.22148

Abstract (EN): Objective: Urogenital tuberculosis and disseminated tuberculosis affecting urogenital system are more fre-quent in developing countries but are often overlooked in developed ones. We aimed to compare clinical characteristics and outcomes of urogenital tuberculosis and disseminated tuberculosis affecting the urogeni-tal system. Material and methods: We retrospectively reviewed data from patients with tuberculosis in the urogenital system, diagnosed in a tertiary center in a European country, from 2008 to 2018. Cases were divided into urogenital tuberculosis and disseminated tuberculosis affecting the urogenital system and compared. Results: We included 172 patients, 31 with urogenital tuberculosis and 141 with disseminated tuberculosis affecting urogenital system. Patients with disseminated tuberculosis affecting the urogenital system were younger (median 45 vs. 64 years, P =.001), more likely to be male (80 vs. 55%, P =.005), or having risk factors for the disease (84 vs. 23%, P =.005) than patients with urogenital tuberculosis. Patients with urogenital tuberculosis presented most commonly with symptoms related to the urinary tract, with 52% complaining of lower urinary tract symptoms attributed to urinary tract infections and 48% of dysuria, while patients with disseminated tuberculosis affecting the urogenital system presented mainly with systemic symptoms, with 89% complaining of malaise, 62% of fever, and 57% of anorexia. Patients with urogenital tuberculosis were more likely to need urological surgery as part of their treatment (71 vs. 5%, P <.001) and patients with disseminated tuberculosis affecting the urogenital system were more likely to die due to tuberculosis (10 vs. 21%, P <.001). Conclusion: Tuberculosis of the urogenital system can have multiple clinical presentations, and a simple diagnostic algorithm does not exist. In the presence of urogenital tuberculosis in injected drug users, immu-nosuppressed individuals, or patients with systemic symptoms, we should think of disseminated tuberculosis affecting the urogenital system and remember these patients less frequently need surgery but entail a worst outcome. © Author(s).

Language: English

Type (Professor's evaluation): Scientific