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Effect of stainless steel corrosion products on in vitro biomineralization

Title
Effect of stainless steel corrosion products on in vitro biomineralization
Type
Another Publication in an International Scientific Journal
Year
1999
Authors
Fernandes MH
(Author)
FMDUP
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Journal
Vol. 14
Pages: 113-168
ISSN: 0885-3282
Publisher: SAGE
Other information
Authenticus ID: P-001-36Z
Abstract (EN): Osteoblast-like cell cultures have been used as in vitro models to study the interactions of bone tissue with biomaterials and their degradation products. This work reviews the effects of AISI 316L stainless steel (SS) corrosion products on the osteoblastic behavior of rat and human bone cell cultures. Results suggest that such products affect, in a dose-]dependent manner, the proliferation and differentiation of osteoblastic cells; these effects depend on the developmental stage of the osteoblastic cells. Above certain nonlethal concentrations, SS corrosion products prevent the mineralization of the extracellular matrix, a process that reflects the complete expression of the osteoblastic phenotype.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 56
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