Go to:
Logótipo
Comuta visibilidade da coluna esquerda
Você está em: Start > Publications > View > Therapeutic nanosystems for oncology nanomedicine
Publication

Publications

Therapeutic nanosystems for oncology nanomedicine

Title
Therapeutic nanosystems for oncology nanomedicine
Type
Article in International Scientific Journal
Year
2012
Authors
Goncalves, AS
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Macedo, AS
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Souto, EB
(Author)
Other
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page Without ORCID
Journal
The Journal is awaiting validation by the Administrative Services.
Vol. 14
Pages: 883-890
ISSN: 1699-048X
Other information
Authenticus ID: P-002-2V7
Abstract (EN): Cancer is a complex disease which includes many pathologies featuring abnormal growth of healthy cells, invasion and metastization. Cellular uncontrolled growth increases the amount of abnormal cells, these cells reach the blood stream and other healthy tissues giving rise to secondary tumors. Even though great progresses have been made in understanding cancer aetiology and in the development of new anticancer drugs, cancer still remains one of the leading causes of death worldwide. Most common cancers include breast cancer, lung cancer, colorectal cancer and brain cancer. Conventional chemotherapeutics have proven to be inefficient in cancer treatment due to lack of specificity and poor drug accumulation in tumors. In addition, they cause severe side effects. Available treatments must be prolonged on time to achieve some therapeutic effect; however, this often leads to the development of multidrug resistance by tumor cells. Nanotechnology platforms are, therefore, being exploited as potential alternatives. Nanosystems have been reported to target and deliver the drug in situ to selectively kill cancer cells, decreasing toxicity on healthy organs and tissues as well as side effects. Furthermore, some nanosystems have been reported to overcome tumor resistance, at least to some extent. Over the years several nanosystems have been proposed to diagnose and treat cancers, such as dendrimers, polymeric micelles, superparamagnetic iron oxide cores, gold nanoparticles, liposomes and other lipid nanoparticles. Due to their small size and biocompatibility, they can reach the target site without being detected by the immune system and suffer cellular uptake or deliver the drug in the tumor vicinity.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 8
Documents
We could not find any documents associated to the publication.
Related Publications

Of the same journal

The prognostic value of MDM2 overexpression in superficial urothelial bladder carcinoma (2002)
Article in International Scientific Journal
Lucio Lara Santos; Pereira, MK; Costa, CS; Amaro, TP; Lameiras, CR; Pereira, SA; Lopes, PS; Alonso, BC; Koch, AC; Lopes, C
Predictive factors for non-sentinel lymph node involvement in breast cancer patients with a positive sentinel node: should we consider sentinel node-related factors? (2009)
Article in International Scientific Journal
Fougo, JL; Afonso, M; Senra, FS; Dias, T; Leal, C; Araujo, C; Mario Dinis Ribeiro
Nanoemulsions and nanoparticles for non-melanoma skin cancer: effects of lipid materials (2013)
Article in International Scientific Journal
Severino, P; Fangueiro, JF; Ferreira, SV; Basso, R; Chaud, MV; Santana, MHA; Rosmaninho, A; Souto, EB
Does body mass index influence surgical options and overall survival in breast cancer patients? (2023)
Article in International Scientific Journal
Luis, C; Fernandes, R; Dias, J; Pereira, D; Machado, F; Baylina, P; Fernandes, R; soares, r
Recommend this page Top
Copyright 1996-2025 © Faculdade de Direito da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z
Page created on: 2025-07-18 at 11:59:40 | Privacy Policy | Personal Data Protection Policy | Whistleblowing