Scalp tumour as a sign of systemic B-cell lymphoma

• Type: Article in International Scientific Journal
• Date: 2004

Authors

magina, s (Author) FMUP; Mesquita Guimaraes, J (Author) Other; Resende, C (Author) Other; Bello, M (Author) Other; Dias C (Author) Other

Journal

Title: Journal of the European Academy of Dermatology and Venereology

Vol. 18

Pages: 196-198

ISSN: 0926-9959

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 6 Citations

Other information

Authenticus ID: P-000-BFA

DOI: 10.1111/j.1468-3083.2004.00784.x

Abstract (EN): An 86-year-old man presented with a painful reddish tumour on the scalp with a 3-month history, mental confusion with recent onset and lymphadenopathies. Histological examination of the lymph node and cutaneous lesion revealed a dense infiltrate of atypical and large B cells. There was no evidence of bone marrow invasion. According to REAL (Revised European-American Classification of Lymphoid Neoplasms), this lymphoma. was considered as a diffuse large B-cell lymphoma with concurrent cutaneous and nodal involvement. Cerebral computerized tomography (CT) scan showed bone and dura mater invasion in the right parieto-occipital region with collapse of lateral ventricle. The patient was submitted to systemic chemotherapy with cyclophosphamide, vincristine and prednisolone (CVP). There was a good response with regression of the cutaneous lesion, but the patient died after the third cycle. We point out the unusual clinical presentation and aggressive behaviour of this lymphoma.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3