Cost-effectiveness analysis of grass pollen specific immunotherapy in children with allergic rhinitis compared to the standard of care symptomatic treatment in Portugal

• Type: Article in International Scientific Journal
• Date: 2023

Authors

Farraia, M (Author) Other; Paciência, I (Author) Other; Mendes, FC (Author) Other; Rufo, JC (Author) Other; Delgado, L (Author) FMUP; Moreira, A (Author) Other

Journal

Title: European Annals of Allergy and Clinical Immunology

Vol. 55

Pages: 212-228

ISSN: 1764-1489

Publisher: EDRA SPA - LSWR Group

Indexing

ISI Web of Knowledge - 2 Citations

Scopus - 2 Citations

Other information

Authenticus ID: P-00X-3W6

DOI: 10.23822/eurannaci.1764-1489.240

Abstract (EN): Background. Cost-effectiveness studies evaluating allergen immunothera-py (AIT) in children are scarce. We aim to compare the cost-effectiveness of subcutaneous (SCIT) and sublingual immunotherapy (SLIT) against stan-dard-of-care (SOC) treatment in children with grass pollen allergic rhinitis. Methods. We created a Markov model to compare the three strategies over a 10-year horizon. SOC was the reference to calculate the incremental cost-ef-fectiveness ratio (ICER). Deterministic and probabilistic sensitivity analysis were used to assess models' uncertainty. Results. We obtained an ICER of 12,605euro and 6,318euro for SLIT and SCIT, respectively. In sensitivity analysis, SCIT was more cost-effective than SLIT. Conclusions. AIT is cost-effective in children with grass pollen allergic rhinitis, especially for the subcutaneous route.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 17