Chemometric-assisted kinetic determination of oxytetracycline using AgInS2 quantum dots as PL sensing platforms

• Type: Article in International Scientific Journal
• Date: 2021

Authors

Castro, RC (Author) Other; Pascoa, RNMJ (Author) Other; Lucia L M F S Saraiva (Author) FFUP; Joao L M Santos (Author) FFUP; Ribeiro, DSM (Author) Other

Journal

Title: Analytica Chimica Acta

Vol. 1188

ISSN: 0003-2670

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 1 Citation

Other information

Authenticus ID: P-00V-M5H

DOI: 10.1016/j.aca.2021.339174

Abstract (EN): In this work a kinetic fluorometric methodology relying on the time-based monitoring of the photo-luminescence quenching of AgInS2 ternary quantum dots induced by oxytetracycline, was developed. The kinetic approach allowed not only to reduce the LOD and improve sensitivity and selectivity but also to collect second-order data that was explored for the quantification of the target analyte in the presence of uncalibrated interfering species. Upon processing the acquired second-order kinetic PL data by unfolded partial least-squares (U-PLS), oxytetracycline was quantified in commercially available pharmaceutical formulations. The obtained results, namely an R-P(2) higher than 0.99 and RE lower than 8%, proved the suitability and accuracy of the developed approach.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10