Blood Cells Separation and Sorting Techniques of Passive Microfluidic Devices: From Fabrication to Applications

• Type: Another Publication in an International Scientific Journal
• Date: 2019

Authors

Catarino, SO (Author) Other; Rodrigues, RO (Author) Other; Pinho, D (Author) Other; Miranda, JM (Author) FEUP; Minas, G (Author) Other; Lima, R (Author) Other

Journal

Title: Micromachines

Vol. 10

Final page: 593

ISSN: 2072-666X

Publisher: MDPI

Indexing

ISI Web of Knowledge - 0 Citations

Scopus - 34 Citations

Other information

Authenticus ID: P-00R-35Y

DOI: 10.3390/mi10090593

Abstract (EN): Since the first microfluidic device was developed more than three decades ago, microfluidics is seen as a technology that exhibits unique features to provide a significant change in the way that modern biology is performed. Blood and blood cells are recognized as important biomarkers of many diseases. Taken advantage of microfluidics assets, changes on blood cell physicochemical properties can be used for fast and accurate clinical diagnosis. In this review, an overview of the microfabrication techniques is given, especially for biomedical applications, as well as a synopsis of some design considerations regarding microfluidic devices. The blood cells separation and sorting techniques were also reviewed, highlighting the main achievements and breakthroughs in the last decades.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 20