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Depression and health-related quality of life in critical COVID-19 survivors

Title
Depression and health-related quality of life in critical COVID-19 survivors
Type
Other Publications
Year
2022
Authors
Silva, J
(Author)
Other
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Martins, S
(Author)
Other
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Ferreira, AR
(Author)
FMUP
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Fernandes, J
(Author)
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Vieira, T
(Author)
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Fontes, L
(Author)
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Reis, N
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Braga, A
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Coimbra, I
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Paiva, J-A
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FMUP
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Lia Fernandes
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FMUP
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Other information
Authenticus ID: P-00X-6BH
Abstract (EN): <jats:sec id="S0924933822009567_sec06061" sec-type="intro"> <jats:title>Introduction</jats:title> <jats:p>Long-term neuropsychiatric consequences of critical illness are well known. Therefore, it is expected that critical COVID-19 patients might also present several psychiatric symptoms such as depression, with inevitable negative effect on health-related quality of life (HRQoL), commonly used as an indicator of illness and treatment impact.</jats:p> </jats:sec> <jats:sec id="S0924933822009567_sec06062"> <jats:title>Objectives</jats:title> <jats:p>To identify depressive symptoms in critical COVID-19 survivors and to examine its association with HRQoL domains.</jats:p> </jats:sec> <jats:sec id="S0924933822009567_sec06063" sec-type="methods"> <jats:title>Methods</jats:title> <jats:p>This preliminary study involved critical COVID-19 patients admitted into the Intensive Care Medicine Department (ICMD) of a University Hospital, between October and December of 2020. Patients with an ICMD length of stay (LoS)¿24h, terminal illness, major auditory loss, or inability to communicate at the follow-up time were excluded. From 1-2 months after discharge, all participants were evaluated by telephone at follow-up appointment, with Patient Health Questionnaire (PHQ-9) (depression) and EuroQol 5-dimension 5-level EQ-5D-5L (HRQoL). This study is part of the longitudinal MAPA project.</jats:p> </jats:sec> <jats:sec id="S0924933822009567_sec06064" sec-type="results"> <jats:title>Results</jats:title> <jats:p>Eighty-three patients were included with a median age of 63 years (range: 31-86) and the majority were male (63%). The most reported problems on EQ-5D-5L domains were usual activities (82%) and mobility (76%). About 27% presented depressive symptoms, and with more problems of self-care (68%vs41%; p=0.029), pain/discomfort (86%vs49%; p=0.002), and anxiety/depression (96%vs54%; p<0.001).</jats:p> </jats:sec> <jats:sec id="S0924933822009567_sec06065" sec-type="conclusions"> <jats:title>Conclusions</jats:title> <jats:p>These preliminary results are in line in previous studies in critical COVID-19 survivors, with depression being associated with worse HRQoL. Bearing this in mind, follow-up approaches with an early screening and treatment of these psychiatric symptoms will be fundamental to optimize the recovery of these patients.</jats:p> </jats:sec> <jats:sec id="S0924933822009567_sec06066"> <jats:title>Disclosure</jats:title> <jats:p>No significant relationships.</jats:p> </jats:sec>
Language: English
Type (Professor's evaluation): Scientific
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