Depression among Endometrial Cancer hospitalizations - Preliminary results of a nationwide retrospective study

• Type: Another Publication in an International Scientific Journal
• Date: 2022

Authors

Vieitol, P (Author) Other; Ferreira, AR (Author) FMUP; Goncalves Pinho, M (Author) FMUP; Costa, F (Author) Other; Coelho, M (Author) Other; Freitas A (Author) FMUP; Lia Fernandes (Author) FMUP

Journal

Title: European Psychiatry

Vol. 65

Pages: S215-S215

ISSN: 0924-9338

Publisher: Cambridge University Press

Indexing

ISI Web of Knowledge - 0 Citations

Other information

Authenticus ID: P-00X-6BG

DOI: 10.1192/j.eurpsy.2022.560

Abstract (EN): <jats:sec id="S0924933822005600_sec02889" sec-type="intro"> <jats:title>Introduction</jats:title> <jats:p>Uterine cancer is the most common gynecologic malignant neoplasm in developed countries. While depression is up to 3-5 times more common in patients with cancer than in the general population, literature is still limited regarding the relation between Endometrial Cancer and depression.</jats:p> </jats:sec> <jats:sec id="S0924933822005600_sec02890"> <jats:title>Objectives</jats:title> <jats:p>To analyze Depression among Endometrial Cancer hospitalizations in mainland Portuguese public hospitals (2008-2015).</jats:p> </jats:sec> <jats:sec id="S0924933822005600_sec02891" sec-type="methods"> <jats:title>Methods</jats:title> <jats:p>A retrospective observational study was conducted using administrative data from all hospitalizations in Portuguese mainland public hospitals between 2008-2015. All women¿s hospitalizations(¿18 years) with a primary diagnosis of Endometrial Cancer (ICD-9-CM 182.x) were selected. Secondary diagnosis of depression was identified with ICD-9-CM 296.2x, 296.3x and 311x codes. Surgical procedures codes 68.4x, 65.6x, 40.3x, 40.5x, 68.6x, 68.9x and 68.8x were used to divide the hospitalizations into surgical vs non-surgical. Groups were compared with Pearson Chi-square test and crude odds ratio(OR) was used to estimate the association between surgery and depression.</jats:p> </jats:sec> <jats:sec id="S0924933822005600_sec02892" sec-type="results"> <jats:title>Results</jats:title> <jats:p>From 10227 hospitalizations with a primary diagnosis of Endometrial Cancer, 533 had a registry of depression(5.2%). Annual depression frequency rose from 2.0% (2008) to 8.3% (2015). Among patients with a record of depression, 73.2% had surgery. Women who had surgery were significantly more likely to have registered depression (p<0.001). The OR for depression in surgical vs non-surgical patients was 1.73 (95%IC:1.42-2.10).</jats:p> </jats:sec> <jats:sec id="S0924933822005600_sec02893" sec-type="conclusions"> <jats:title>Conclusions</jats:title> <jats:p>Patients hospitalized due to Endometrial Cancer and submitted to surgery had almost two-fold more risk of having a registry of depression. This trend reinforces the importance of early depression screening of these patients, enabling the implementation of timely therapeutic strategies before and after surgery.</jats:p> </jats:sec> <jats:sec id="S0924933822005600_sec02894"> <jats:title>Disclosure</jats:title> <jats:p>No significant relationships.</jats:p> </jats:sec>

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 1