Reduced graphene oxide-nickel nanoparticles/biopolymer composite films for the sub-millimolar detection of glucose

• Type: Article in International Scientific Journal
• Date: 2016

Authors

Krishna, R (Author) Other; Jose M Campina (Author) FCUP; Fernandes, PMV (Author) Other; ventura, j. (Author) FCUP; Titus, E (Author) Other; Silva, F (Author) FCUP

Journal

Title: The Analyst

Vol. 141

Pages: 4151-4161

ISSN: 0003-2654

Publisher: Royal Society of Chemistry

Indexing

ISI Web of Knowledge - 7 Citations

Scopus - 9 Citations

Other information

Authenticus ID: P-00K-KQ3

DOI: 10.1039/c6an00475j

Abstract (EN): Hybrid conjugates of graphene with metallic/semiconducting nanostructures can improve the sensitivity of electrochemical sensors due to their combination of well-balanced electrical/electrocatalytic properties and superior surface-to-volume ratio. In this study, the synthesis and physical characterization of a hybrid conjugate of reduced graphene oxide and nickel nanoparticles (rGO-Ni NPs) is presented. The conjugate was further deposited onto a glassy carbon electrode as a nanocomposite film of chitosan and glucose oxidase. The electrochemical response and morphology of the films were investigated using SEM, CV, and EIS, and their applications as a glucose biosensor explored for the first time in proof-of-concept tests. The low operating potential along with the good linearity and sensitivity (up to 129 mu A cm(-2) mM(-1)) found in the sub-millimolar range suggest potential applications in the self-management of hypoglycemia from blood samples or in the development of non-invasive assays for body fluids such as saliva, tears or breath.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 11