Detection of cell nuclei on sequences of confocal microscopy images

• Type: Article in International Conference Proceedings Book
• Date: 2008

Authors

Tiago Guichard (Author) Other; Ana Maria Mendonça (Author) FEUP

Conference proceedings National

Title: Actas do RecPad 2008

Pages: 1-2

RecPad 2008

Coimbra - Portugal, 31 de Outubro de 2008

Scientific classification

FOS: Engineering and technology > Electrical engineering, Electronic engineering, Information engineering

Other information

Abstract (EN): This paper presents a method to perform automated detection of cell nuclei. The method starts with a filtering operation aiming at enhancing the image areas that may correspond to nuclei. The enhanced image local maxima can be associated with the potential locations of cell nuclei, but the filter responses also give additional positional information that can be related with nucleus borders, thus allowing the approximation of each nucleus contour by an ellipse. Afterwards, an analysis of the detected areas allows their validation or removal, as well as the adjustment of the final contours in order to facilitate the splitting of some nuclei that were overlapped because they belong to different cell layers.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 2