A clinical report of bone regeneration in maxillofacial surgery using Bonelike (R) synthetic bone graft

• Type: Article in International Scientific Journal
• Date: 2008

Authors

Sousa, RC (Author) Other; Lobato, JV (Author) Other; Mauricio, AC (Author) ICBAS; Hussain, NS (Author) Other; Botelho, CM (Author) Other; Lopes, MA (Author) FEUP; Santos, JD (Author) FEUP

Journal

Title: Journal of Biomaterials Applications

Vol. 22

Pages: 373-385

ISSN: 0885-3282

Publisher: SAGE

Indexing

ISI Web of Knowledge - 19 Citations

ISI Web of Science

Scopus - 20 Citations

Scientific classification

FOS: Engineering and technology > Environmental biotechnology

Other information

Authenticus ID: P-004-3SV

DOI: 10.1177/0885328207078260

Abstract (EN): The objective of this study is to evaluate the osteoconductivity and bioactivity of the Bonelike (R) graft in repairing surgical cystic bone defects. Bonelike (R) is implanted in 11 patients, aged between 24 and 53 years with a mean age of 36 years, consisting of 5 men and 6 women. According to the standard follow up protocols, radiological examinations are performed and Bonelike (R)/bone retrieved samples have been analyzed histologically using non-decalcified sections obtained perpendicular to bone length axis. Radiographic examination and histological results clearly demonstrate an extensive new bone formation apposed on Bonelike (R) granules with a Significant degree of maturation. These clinical applications in maxillary bone defects indicate perfect bone bonding between new bone formed and Bonelike (R) granules, along with partial surface biodegradation. This quick and effective osteoconductive response from Bonelike (R) may reduce the time needed to reconstruct the bone defected area of patients.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 13