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Cationic Antimicrobial Peptides for Tuberculosis: A Mini-Review

Title
Cationic Antimicrobial Peptides for Tuberculosis: A Mini-Review
Type
Another Publication in an International Scientific Journal
Year
2019
Authors
Silva, S
(Author)
Other
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Nuno Vale
(Author)
ICBAS
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Journal
Vol. 20
Pages: 885-892
ISSN: 1389-2037
Publisher: Bentham Science
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Publicação em ISI Web of Knowledge ISI Web of Knowledge - 0 Citations
Publicação em Scopus Scopus - 0 Citations
Other information
Authenticus ID: P-00R-3QA
Abstract (EN): Cationic antimicrobial peptides (CAMPs) can be considered as new potential therapeutic agents for Tuberculosis treatment with a specific amino acid sequence. New studies can be developed in the future to improve the pharmacological properties of CAMPs and also understand possible resistance mechanisms. This review discusses the principal properties of natural and/or synthetic CAMPs, and how these new peptides have a significant specificity for Mycobacterium tuberculosis. Also, we propose some alternative strategies to enhance the therapeutic activity of these CAMPs that include co-administration with nanoparticles and/or classic drugs.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 8
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