Gut microbiota and age-related macular degeneration: A growing partnership

• Type: Article in International Scientific Journal
• Date: 2022

Authors

Lima-Fontes, M (Author) Other; Meira, L (Author) Other; Barata, P (Author) Other; Manuel Falcão (Author) FMUP; Ângela Carneiro (Author) FMUP

Journal

Title: Survey of Ophthalmology

Vol. 67

Pages: 883-891

ISSN: 0039-6257

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 4 Citations

Other information

Authenticus ID: P-00V-RKV

DOI: 10.1016/j.survophthal.2021.11.009

Abstract (EN): Age-related macular degeneration (AMD) is a leading cause of severe, irreversible vision impairment in developed countries, and its prevalence is rising all over the world, increasing sharply with age. AMD represents an acquired degeneration of the retina that causes significant central visual impairment through a combination of noneovascular and neovascular derangement. The main risk factors for the development of advanced AMD are increasing age, genetic factors, and cigarette smoking; however, the exact pathophysiology of AMD is yet relatively poorly understood. In recent years, the gut microbiota has been intensively studied and linked to several pathologic processes, including ocular diseases. In this sense, the aim of this review is to gather published evidence about the relationship between gut microbiota and AMD.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9