Immediate Reactions to Fluorescein and Indocyanine Green in Retinal Angiography: Review of Literature and Proposal for Patient's Evaluation

• Type: Another Publication in an International Scientific Journal
• Date: 2020

Authors

Meira, J (Author) Other; Marques, ML (Author) Other; Falcão-Reis F (Author) FMUP; Gomes, ER (Author) Other; Ângela Carneiro (Author) FMUP

Journal

Title: Clinical Ophthalmology

Vol. 14

Pages: 171-178

ISSN: 1177-5467

Publisher: Dove Medical Press

Indexing

ISI Web of Knowledge - 11 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-00R-NH9

DOI: 10.2147/opth.s234858

Abstract (EN): Introduction: Contrast rapid sequence angiography with fluorescein or indocyanine green (ICG) is a diagnostic procedure commonly used in ophthalmology. Adverse reactions to fluorescein and ICG are rare and may be classified as toxic, of hypersensitivity and non-specific. The evaluation and management of a patient with an adverse reaction is a challenge for the majority of ophthalmologists, as is the assessment of risk factors that may contraindicate the procedure. Purpose: We aim to review the concepts underlying adverse reactions to fluorescein and ICG, especially those of hypersensitivity, and present a proposal or the evaluation of the patients in need to perform retinal angiography and for the treatment of immediate reactions to fluorescein and ICG. Methods: The available literature was examined using PubMed-Medline, and using the MeSH terms "fluorescein", "Indocyanine green", "ophthalmic dyes", "retinal angiography", "adverse reactions", and "allergic reaction". Conclusion: This review may help ophthalmologists to identify patients with higher risk of a hypersensitivity reaction and give them tools to recognize patients with suspected hypersensitivity that may benefit from an allergy study.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 8