Need for refining successful revascularization in endovascular treatment of acute ischemic stroke: Data from real-world

• Type: Article in International Scientific Journal
• Date: 2018

Authors

Carvalho, A (Author) Other; Samos, T (Author) Other; Cunha, A (Author) Other; Gregorio, T (Author) Other; Paredes, L (Author) Other; Costa, H (Author) Other; Castro, S (Author) Other; Ribeiro, M (Author) Other; Veloso, M (Author) Other; Barros, P (Author) Other

Journal

Title: Journal of the Neurological Sciences

Vol. 384

Pages: 129-132

ISSN: 0022-510X

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 14 Citations

Other information

Authenticus ID: P-00N-KR9

DOI: 10.1016/j.jns.2017.10.013

Abstract (EN): Introduction: Modified TICI (mTICI) score >= 2b has been largely used as a definition of successful revascularization in acute stroke endovascular treatment (EVT). However, mTICI 2b encompasses a broad range of different revascularization states and its clinical relevance, comparing to mTICI 3, has been questioned. We aimed to compare clinical outcomes between these two reperfusion groups, in patients submitted to EVT for anterior circulation large-vessel occlusion, in a real-world setting. Materials and methods: Retrospective statistical analysis of our database of consecutive EVTs. Results: Our study population of 178 patients has a mean age of 71 years, 46.6% males, median baseline NIHSS of 17 and ASPECTS of 8. There were no statistically significant differences in baseline characteristics and interventional procedure data between groups. A significantly higher rate of mRS <= 1 at 3 months (OR = 2.33, 95%CI 1.03-5.25) and lower rate of total (OR = 0.18, 95%CI 0.06-0.53) and symptomatic intracranial hemorrhage (OR = 0.08, 95% CI 0.01-0.74) was seen in mTICI 3 group. This group also showed non -significant trend (adjustedp = 0.071) toward higher percentages of mRS <= 2 (71.8% versus 51.5%) and lower mortality at 3 months (6.4% versus 19.1%). Conclusions: In accordance with previous reports from clinical trials, these real -world data suggest that is probably time to refine the definition of successful revascularization in acute stroke EVT.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4