Endovascular Stroke Treatment of Patients Over 80 Years Old: Cumulative Evidence from the "Real World"

• Type: Article in International Scientific Journal
• Date: 2017

Authors

Figueiredo, S (Author) Other; Carvalho, A (Author) Other; Rodrigues, M (Author) Other; Cunha, A (Author) Other; Paredes, L (Author) Other; Costa, H (Author) Other; Barros, P (Author) Other; Gregorio, T (Author) Other; Ribeiro, M (Author) Other; Castro, S (Author) Other; Veloso, M (Author) Other

Journal

Title: Journal of Stroke and Cerebrovascular Diseases

Vol. 26

Pages: 2949-2953

ISSN: 1052-3057

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 9 Citations

Scopus - 10 Citations

Other information

Authenticus ID: P-00N-A4H

DOI: 10.1016/j.jstrokecerebrovasdis.2017.07.020

Abstract (EN): Background: Evidence on stent retriever-based thrombectomy (SRT) efficacy in elderly patients is controversial. This study aimed to analyze safety and efficacy outcomes in octogenarians submitted to SRT. Methods: Analysis was based on a prospective observational registry of patients with stroke because of anterior circulation large-vessel occlusion treated with SRT at our center between January 2015 and September 2016. Patients were dichotomized into 2 age groups: <= 80 and >80 years old. Outcomes at 90 days were assessed: "excellent outcome" (a modified Rankin scale [mRs] score of 0-1) and "good outcome" (a mRs score of 0-2). Results: A total of 141 patients were included: 35 (24.8%) >80 years old and 106 (71.2%) <= 80 years old; 43.4% of patients in the younger group and 25.7% of patients in the older group achieved an "excellent outcome." A "good outcome" was achieved in 65.1% of patients in the younger group, and 60% of patients in the older group; crude odds ratio (OR) for "excellent outcome" was 0.452 (P = .067). Crude OR for "good outcome" was 0.804 (P = .587). After adjusting for gender, National Institutes of Health Stroke Scale score at admission, Alberta Stroke Program Early CT Score, and thrombolysis, the OR was 0.450 (P = .100) and 1.217 (P = .686) for "excellent" and "good" outcomes, respectively. Conclusions: In this cohort, 60% of elderly patients regained functional independence at 3 months after SRT. Although age may be a prognostic factor, patients should not be excluded from SRT based on age criteria.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 5