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Prediction of success of uterus-preserving management in women with placenta accreta spectrum (CON-PAS score): A multicenter international study

Title
Prediction of success of uterus-preserving management in women with placenta accreta spectrum (CON-PAS score): A multicenter international study
Type
Article in International Scientific Journal
Year
2021
Authors
Shazly, SA
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Hortu, I
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Shih, JC
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Melekoglu, R
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Fan, SR
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ul Ain Ahmed, F
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Karaman, E
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Fatkullin, I
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Pinto, PV
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FMUP
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Irianti, S
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Tochie, JN
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Abdelbadie, AS
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Salah, MA
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Abd Elazeem, HAS
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Saad, MM
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Ergenoglu, AM
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Yeniel, AO
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Sagol, S
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Itil, IM
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Kang, J
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Huang, KY
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Yilmaz, E
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Liang, YH
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Aziz, H
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Akhter, T
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Ambreen, A
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Ates, C
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Karaman, Y
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Khasanov, A
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Fatkullina, L
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Akhmadeev, N
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Vatanina, A
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Machado, AP
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Montenegro, N
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Effendi, JS
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Suardi, D
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Pramatirta, AY
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Aziz, MA
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Siddiq, A
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Ofakem, I
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Dohbit, JS
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Fahmy, MS
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Anan, MA
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Journal
Vol. 154
Pages: 304-311
ISSN: 0020-7292
Publisher: Wiley-Blackwell
Other information
Authenticus ID: P-00T-MMC
Resumo (PT):
Abstract (EN): Objective To create a model for prediction of success of uterine-preserving procedures in women with placenta accreta spectrum (PAS). Methods PAS-ID is a multicenter study that included 11 centers from 9 countries. Women with PAS, who were managed between January 1, 2010 and December 31, 2019, were retrospectively included. Data were split into model development and validation cohorts, and a prediction model was created using logistic regression. Main outcome was success of uterine preservation. Results Out of 797 women with PAS, 587 were eligible. Uterus-preserving procedures were successful in 469 patients (79.9%). Number of previous cesarean sections (CS) was inversely associated with management success (adjusted odds ratio [aOR] 0.02, 95% confidence interval [CI] 0.001-3.63 with five previous CS). Other variables were complete placental invasion (aOR 0.14, 95% CI 0.05-0.43), type of CS incision (aOR 0.04, 95% CI 0.01-0.25 for classical incision), compression sutures (aOR 2.48, 95% CI 1.00-6.16), accreta type (aOR 3.76, 95% CI 1.13-12.53), incising away from placenta (aOR 5.09, 95% CI 1.52-16.97), and uterine resection (aOR 102.57, 95% CI 3.97-2652.74). Conclusion The present study provides a prediction model for success of uterine preservation, which may assist preoperative and intraoperative decisions, and promote incorporation of uterine preservation procedures in comprehensive PAS protocols.
Language: English
Type (Professor's evaluation): Dissemination
No. of pages: 8
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