Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium

• Type: Article in International Scientific Journal
• Date: 2022

Authors

de la Hera, MG (Author) Other; Lpez Carrillo, L (Author) Other; Hernndez Ramrez, RU (Author) Other; Hamada, GS (Author) Other; Ward, MH (Author) Other; Mu, L (Author) Other; Malekzadeh, R (Author) Other; Pourfarzi, F (Author) Other; Trichopoulou, A (Author) Other; Karakatsani, A (Author) Other; Kurtz, RC (Author) Other; Lagiou, A (Author) Other; Lagiou, P (Author) Other; Boccia, S (Author) Other; Boffetta, P (Author) Other; Camargo, MC (Author) Other; Negri, E (Author) Other; La Vecchia, C (Author) Other; Martimianaki, G (Author) Other; Alicandro, G (Author) Other; Pelucchi, C (Author) Other; Bonzi, R (Author) Other; Rota, M (Author) Other; Hu, JF (Author) Other; Johnson, KC (Author) Other; Rabkin, CS (Author) Other; Liao, LM (Author) Other; Sinha, R (Author) Other; Zhang, ZF (Author) Other; Dalmartello, M (Author) Other; Lunet N (Author) FMUP; Morais, S (Author) Other; Palli, D (Author) Other; Ferraroni, M (Author) Other; Yu, GP (Author) Other; Tsugane, S (Author) Other; Hidaka, A (Author) Other; Curado, MP (Author) Other; Dias Neto, E (Author) Other; Zaridze, D (Author) Other; Maximovitch, D (Author) Other; Vioque, J (Author) Other

Journal

Title: British Journal of Cancer

Vol. 127

Pages: 726-734

ISSN: 0007-0920

Publisher: Springer Nature

Indexing

ISI Web of Knowledge - 1 Citation

Scopus - 1 Citation

Other information

Authenticus ID: P-00W-MVZ

DOI: 10.1038/s41416-022-01856-w

Abstract (EN): Background Evidence from epidemiological studies on the role of tea drinking in gastric cancer risk remains inconsistent. We aimed to investigate and quantify the relationship between tea consumption and gastric cancer in the Stomach cancer Pooling (StoP) Project consortium. Methods A total of 9438 cases and 20,451 controls from 22 studies worldwide were included. Odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) of gastric cancer for regular versus non-regular tea drinkers were estimated by one and two-stage modelling analyses, including terms for sex, age and the main recognised risk factors for gastric cancer. Results Compared to non-regular drinkers, the estimated adjusted pooled OR for regular tea drinkers was 0.91 (95% CI: 0.85-0.97). When the amount of tea consumed was considered, the OR for consumption of 1-2 cups/day was 1.01 (95% CI: 0.94-1.09) and for >3 cups/day was 0.91 (95% CI: 0.80-1.03). Stronger inverse associations emerged among regular drinkers in China and Japan (OR: 0.67, 95% CI: 0.49-0.91) where green tea is consumed, in subjects with H. pylori infection (OR: 0.68, 95% CI: 0.58-0.80), and for gastric cardia cancer (OR: 0.64, 95% CI: 0.49-0.84). Conclusion Our results indicate a weak inverse association between tea consumption and gastric cancer.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 9