Living-donor Kidney Transplantation: Predictive Factors and Impact on Post-transplant Outcome

• Type: Article in International Scientific Journal
• Date: 2015

Authors

Araujo, AM (Author) Other; Santos, F (Author) Other; Guimaraes, J (Author) Other; Nunes, CS (Author) Other; Casal, M (Author) Other

Journal

Title: Transplantation Proceedings

Vol. 47

Pages: 938-941

ISSN: 0041-1345

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 2 Citations

Scopus - 0 Citations

Other information

Authenticus ID: P-00G-60G

DOI: 10.1016/j.transproceed.2015.04.001

Abstract (EN): Renal transplantation from living donors represents a valuable opportunity for patients with end-stage renal disease due to short- and long-term outcomes. Nevertheless, it requires that a detailed set of conditions be considered for donor and recipient selection, with possible implications arising from these criteria in the post-transplant outcome. The present work aims to study demographic and clinical characteristics of donors and kidney recipients that predict post-transplantation outcomes after living donor kidney transplantation. With this aim, all patients who underwent donor nephrectomy and living donor transplantation between January 2012 and December 2013 were selected. Demographics, medical comorbidities, and postoperative outcomes were transcribed from electronic patient records. Linear and logistic regressions were applied for data analysis. The study sample consists of 40 patients who underwent living donor kidney transplantation. The presence of peripheral arterial disease and the etiology of end-stage renal disease were the only pretransplant variables that seem to independently predict hospitalization time. Simultaneously, the occurrence of urorenal and infectious complications had a statistically significant correlation with hospitalization time. Additionally, the incidence of cardiovascular complications was correlated with surgical reinterventions at a significant level. The results suggest that careful selection of the donor and the kidney recipient appears to be a prerequisite for a successful transplantation in vivo.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4