Fixed drug eruption by etoricoxib confirmed by patch test

• Type: Article in International Scientific Journal
• Date: 2016

Authors

de Sousa, AS (Author) Other; Cardoso, JC (Author) Other; Gouveia, MP (Author) Other; Gameiro, AR (Author) Other; Teixeira, VB (Author) Other; Goncalo, M (Author) Other

Journal

Title: Anais Brasileiros de Dermatologia

Vol. 91

Pages: 652-654

ISSN: 0365-0596

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 5 Citations

Scopus - 8 Citations

Other information

Authenticus ID: P-00M-6T5

DOI: 10.1590/abd1806-4841.20164301

Abstract (EN): Non-steroidal, anti-inflammatory drugs, followed by antibiotics, are the main causes of fixed drug eruption. They provoke one or several round erythematous or bullous lesions that recur in the same place after taking the causative medication. A positive patch test on residual, lesional skin can replace satisfactorily oral reintroduction. We describe the case of a 74-year-old woman with numerous, rounded, erythematous lesions on the trunk and recurrent blistering on the fifth right-hand finger, which developed a few hours after taking etoricoxib. Lesional patch testing with etoricoxib was positive and reproduced the typical pattern of a fixed drug eruption upon histopathology. We emphasize the specific reactivity of the etoricoxib patch test, and the capacity to reproduce the histologic pattern of the reaction.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3