Linear Lupus Erythematosus Profundus as an Initial Manifestation of Systemic Lupus Erythematosus in a Child

• Type: Article in International Scientific Journal
• Date: 2014

Authors

Fernandes, S (Author) Other; Santos, S (Author) Other; Freitas, I (Author) Other; Salgado, M (Author) Other; Afonso, A (Author) Other; Cardoso, J (Author) Other

Journal

Title: Pediatric Dermatology

Vol. 31

Pages: 378-380

ISSN: 0736-8046

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 6 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-009-B26

DOI: 10.1111/pde.12014

Abstract (EN): The case of a 13-year-old Caucasian girl with a 1-year history of a linear plaque on her thigh is reported. Histopathologic examination of the incisional biopsy tissue established the diagnosis of lupus erythematosus panniculitis. Six months later she developed the clinical and laboratory criteria for the diagnosis of systemic lupus erythematosus (SLE). She was treated with azathioprine and oral prednisolone, with a favorable clinical outcome. Our case illustrates a child with linear lupus erythematosus profundus as an initial manifestation of SLE. To our knowledge, only eight other cases of linear lupus erythematosus profundus have been reported in the literature, five in children. In contrast to our patient, none of those cases progressed to SLE during the reported follow-up period. The authors report this case to illustrate an unusual superimposed segmental manifestation of an inflammatory polygenic disorder.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3