Sex-related inequalities in management of patients with acute coronary syndromeresults from the EURHOBOP study

• Type: Article in International Scientific Journal
• Date: 2018

Authors

Araujo, C (Author) Other; Pereira, M (Author) Other; Laszczynska, O (Author) Other; Dias, P (Author) Other; Azevedo A (Author) FMUP

Journal

Title: International Journal of Clinical Practice

Vol. 72

ISSN: 1368-5031

Publisher: Wiley-Blackwell

Indexing

ISI Web of Knowledge - 6 Citations

Other information

Authenticus ID: P-00N-JCD

DOI: 10.1111/ijcp.13049

Abstract (EN): BackgroundReal-world data from different levels of hospital specialisation would help to understand if differences in management between women and men with acute coronary syndrome (ACS) are still a priority target. We aimed to identify sex inequalities in management of patients with different types of ACS. MethodsWe analysed 1757 patients with a non-ST-elevation ACS (NSTEACS) and 1184 with ST elevation myocardial infarction (STEMI) or left bundle branch block (non-classifiable (NC) ACS (STEMI/NC ACS group), consecutively discharged from ten Portuguese hospitals with different specialisation levels, between 2008 and 2010. We estimated odds ratios (OR) and 95% confidence intervals (95% CI) for the association between sex and the performance of coronary angiography, reperfusion and revascularisation. ResultsAmong STEMI/NC ACS, men had higher probability of performing coronary angiography than women (adjusted OR=1.64, 95% CI: 1.11-2.44), while among NSTEACS patients there was no significant difference by sex (adjusted OR=1.26, 95% CI: 0.99-1.62). In patients who underwent coronary angiography, there was no difference in proportion of women and men submitted to revascularisation, regardless of the ACS type. Although men with STEMI/NC ACS were more likely to undergo reperfusion (crude OR=2.17, 95% CI: 1.68-2.81), the effect became not significant after multivariable adjustment (adjusted OR=1.33, 95% CI: 0.96-1.84). ConclusionWomen diagnosed with STEMI/NC, but not NSTEACS, had lower probability when compared with men to be submitted to coronary angiography. There was no difference in performance of reperfusion and revascularisation by sex.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 10