Evaluation of the efficacy of deep brain stimulation in the surgical treatment of cervical dystonia

• Type: Article in International Scientific Journal
• Date: 2014-04

Authors

Paulo Linhares (Author) FMUP

Journal

Title: Neurocirugia

Vol. 25

Pages: 49-55

ISSN: 1130-1473

Publisher: Sociedad Espanola de Neurocirugia

Indexing

ISI Web of Knowledge - 4 Citations

Scopus - 4 Citations

Other information

Authenticus ID: P-009-B5Y

DOI: 10.1016/j.neucir.2013.10.004

Abstract (EN): Objective: Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a promising therapeutic option for patients with medically refractory dystonia. We present the results after 1 year of DBS of the GPi in 4 patients with cervical dystonia. Materials and methods: Four patients with medically refractory cervical dystonia who underwent stereotactic pallidal DBS surgery between June 2010 and November 2011 were included in this retrospective study. Preoperative and postoperative evaluations at 3, 6 and 12 months after surgery were performed using the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS). Results: The 4 patients experienced a sustained improvement, with a mean TWSTRS reduction of 74.25%, at 12 months follow-up. Disability improved by 80.5% (mean) at 1 year follow-up. No stimulation-related side effects were reported. Conclusion: Pallidal DBS is a valid and effective second-line treatment for patients with cervical focal dystonia. Our results support its use in patients with an insufficient response to medical treatment. (C) 2013 Sociedad Espanola de Neurocirugia. Published by Elsevier Espana, S.L. All rights

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 7