Bilateral Angle Narrowing and Acute Myopia Induced by Indapamide: A Case Report

• Type: Article in International Scientific Journal
• Date: 2018

Authors

Pedrosa, AC (Author) Other; Araujo, JR (Author) Other; Macedo, JP (Author) Other; Silva, SE (Author) Other; Melo, A (Author) Other; Falcao Reis, F (Author) Other

Journal

Title: CASE REPORTS IN OPHTHALMOLOGICAL MEDICINE

Vol. 2018

Pages: 1-4

ISSN: 2090-6722

Indexing

ISI Web of Knowledge - 0 Citations

Other information

Authenticus ID: P-00Q-1DH

DOI: 10.1155/2018/1486128

Abstract (EN): Purpose. To describe a clinical case of indapamide induced bilateral angle narrowing and acute myopia. Materials and Methods. Clinical case report. Results. A 37-year-old Caucasian emmetropic man presented to the Emergency Department with complaints of acute-onset bilateral blurry vision, nine days after starting treatment for arterial hypertension with a combination of indapamide and amlodipine. Clinical examination revealed the presence of myopia and appositional closure of the anterior chamber angle. Ultrasound biomicroscopy and mode B ultrasonography disclosed bilateral ciliochoroidal effusion with anterior rotation of the ciliary body and iridocorneal angle narrowing. After intraocular pressure control with brimonidine and timolol, and replacement of indapamide/amlodipine by amlodipine only, the patient was discharged. Complete resolution of the clinical manifestations was observed after three weeks, with no sequelae. Conclusions. Indapamide may cause acute myopia and angle closure secondary to ciliochoroidal effusion that are fully reversible after drug withdrawal, as long as timely diagnosis is established. Therefore, indapamide, as well as other sulfonamide-derived drugs, must always be considered in the differential diagnosis of acute myopia and angle closure.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 4