Imported dengue from 2013 Angola outbreak: Not just serotype 1 was detected

• Type: Article in International Scientific Journal
• Date: 2016

Authors

Abreu, C (Author) FMUP; Silva Pinto, A (Author) FMUP; Lazzara, D (Author) Other; Sobrinho Simoes, J (Author) Other; guimaraes, jt (Author) FMUP; Sarmento A (Author) FMUP

Journal

Title: Journal of Clinical Virology

Vol. 79

Pages: 77-79

ISSN: 1386-6532

Publisher: Elsevier

Indexing

ISI Web of Knowledge - 12 Citations

Scopus - 11 Citations

Other information

Authenticus ID: P-00K-CN2

DOI: 10.1016/j.jcv.2016.04.011

Abstract (EN): Background: All the reports from Angola's 2013 dengue outbreak revealed serotype 1. However, previously dengue serotypes 1-4 have been reported in Africa and in 2014 serotype 4 was reported in Angola. Objectives: To report dengue serotypes in patients returning from Angola during 2013 outbreak. Study design: Retrospective, cross-sectional study. We serotyped the dengue by an in house Polymerase Chain Reaction technique in randomly selected cases. Results: From the 2013 Angola's dengue outbreak we treated 47 adult patients. None had history of past dengue. A combo kit test for dengue revealed positive NS1 antigen in 39 and IgM antibodies in 8. From 17 randomly patients tested by RNA Real Time-PCR, 11 were positive: 7 for DENY-1,2 for DENV-2, 1 for DENV-3 (co-infected with DENY-1) and 1 for DENV-4. None had a complicated or fatal evolution. Conclusion: Unlike previous reports the 4 serotypes were detected, and this resulted in a different epidemiological situation, raising the risk of future outbreaks of severe dengue.

Language: English

Type (Professor's evaluation): Scientific

No. of pages: 3